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Image Search Results
Journal: eLife
Article Title: State-dependent representations of mixtures by the olfactory bulb
doi: 10.7554/eLife.76882
Figure Lengend Snippet: ( A ) Reward contingencies used to achieve different behavioural states in awake mice. Top: mice were trained to discriminate between odours with ethyl butyrate (EB) vs. odours without EB. Middle: naïve mice received water reward 3 s after the onset of odour, on randomly selected trials. Bottom: naïve mice received water every trial, 15 s before odour onset. ( B ) Sniff patterns associated with trained and behaving mice (black), naïve and engaged mice (orange), and naïve and disengaged mice (light blue). Speed of inhalation during odour presentations shown. ( C ) Comparison of support vector machine (SVM) performance using data from behaving mice (black) vs. naïve engaged mice (left panel, orange), and vs. naïve disengaged mice (right panel, light blue). SVM was trained to discriminate responses to S+ vs. S- odours using randomly selected 80% of trials and tested on the remaining 20% of the trials. ( D ) Decoder performance for the results in ( C ) plotted using approximate z-values obtained from MATLAB implementation of Wilcoxon rank-sum test. ( E ) As in ( C ), but SVM was trained using responses to single odours, and tested on mixture responses. ( F ) As in ( D ) but for the results in ( E ). n = 13 fields of view, six mice for behaving, 17 fields of view, six mice for naïve, engaged, and 14 sessions, four mice for naïve, disengaged mice. See for linearity of summation.
Article Snippet: For testing the effect of trial-by-trial variability, Gaussian noise was generated using the
Techniques: Comparison, Plasmid Preparation